Table 3. Pulmonary inflammation at the end of the 120-min reperfusion period.
Group | TNF-α (pg/ml) | MPO Activity (ΔOD/g/min) | Wet/Dry Weight |
---|---|---|---|
Control | 1336 ± 18.9 | 0.858 ± 0.012 | 3.07 ± 0.08 |
A1 agonist | 759 ± 14.7 a, b | 0.582 ± 0.013 a, b | 2.22 ± 0.05 a |
A1 agonist + antagonist | 1308 ± 18.7 b | 0.810 ± 0.015 b | 2.98 ± 0.09 b |
A2A agonist | 804 ± 17.6 a, b | 0.482 ± 0.017 a, b, c | 2.08 ± 0.05 a |
A2A agonist + antagonist | 1326 ± 18.7 b | 0.847 ± 0.026 b | 2.90 ± 0.18 b |
A3 agonist | 778 ± 10.5 a, b | 0.540 ± 0.016 a, b | 2.03 ± 0.08 a |
A3 agonist + antagonist | 1287 ± 13.8 b | 0.843 ± 0.150 b | 3.00 ± 0.06 b |
Adenosine | 978 ± 26.0 a | 0.697 ± 0.028 a | 2.41 ± 0.06 a |
p<0.0002 vs. Control,
p<0.01 vs. Adenosine,
p<0.01 vs. A1 agonist