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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Kidney Int. 2010 May 5;78(3):279–286. doi: 10.1038/ki.2010.132

Figure 1.

Figure 1

Plasma C3 levels in Cfh−/− mice injected with hCFH. (A) and (B) Mouse serum C3 levels at different time points following a single intraperitoneal injection of either 0.5mg hCFH (filled circles) or an equivalent volume of PBS (open circles). (A) and (B) represent two separate experiments. Horizontal bars denote median values. Asterisk (*) denotes p=0.0286, Mann Whitney test. In this ELISA pooled normal wild-type C3 level was 420 mg/l. (C) representative western blot of sera under reducing conditions for C3 from a Cfh−/− animal injected with hCFH. (D) Serum hCFH levels following single intraperitoneal injection of 0.5mg hCFH in to Cfh−/− (n=4, squares, solid line) and Cfh−/−.C3−/− (n=3, triangles, dotted line) mice. Data points represent mean +/− standard deviation. Asterisk (*) denotes p<0.05, Student t test.