Table 3.
DNA damage-, oxidative stress-induced and DNA repair genes over-expressed in the 8-month-old mouse spermatogonial stem cell/progenitor cells.
Probe ID | Gene symbol | Description | Fold changea |
---|---|---|---|
1450971_at | Gadd45b | Growth arrest and DNA-damage-inducible 45β | 11.8 |
1444184_at | Alkbh3 | alkB, alkylation repair homolog 3 (Escherichia coli) | 7.7 |
1441568_at | Osgin2 | Oxidative stress-induced growth inhibitor family member 2 | 5.0 |
1453539_at | Alkbh8 | alkB, alkylation repair homolog 8 (E. coli) | 3.7 |
1428306_at | Ddit4 | DNA-damage-inducible transcript 4 | 3.3 |
1451751_at | Ddit4l | DNA-damage-inducible transcript 4-like | 3.0 |
1450935_at | Ercc5 | Excision repair cross-complementing rodent repair deficiency 5 | 2.6 |
1437447_s_at | Ercc1 | Excision repair cross-complementing rodent repair deficiency 1 | 2.5 |
1429850_x_at | Alkbh4 | alkB, alkylation repair homolog 4 (E. coli) | 2.5 |
1451928_a_at | Rad18 | RAD18 homolog (S. cerevisiae) | 2.4 |
Fold change represents the change in transcript levels between GFRA1-positive and GFRA1-negative cells in the 8-month-old age group. No significant change has been observed by microarray analysis for these genes in the other younger age groups.