Table 1. Methylation of the DUSP16 CpG island in B cell neoplasia.
| Cell line | Origin | EBV | DUSP16 methylation (MSP) |
|---|---|---|---|
| AW Ramos | Endemic | + | +/− |
| BL2 | Sporadic | − | − |
| BL41 | Sporadic | − | + |
| Dante | Sporadic | + | + |
| DG75 | Sporadic | − | +/− |
| Mak-I | Not known | + | +/− |
| Mutu | Endemic | + | +/− |
| Rael | Sporadic | + | + |
| Ramos | Endemic | − | +/− |
| Tissue | Origin | DUSP16 methylation (MSP) | |
| DLBCL | 0/10 | ||
| FL | 0/10 | ||
| MCL | 0/10 | ||
| MZL | 0/10 | ||
| BL | Endemic | 27/45 | |
| BL | Sporadic | 2/8 | |
| BL | HIV-associated | 2/4 | |
Abbreviations: BL=Burkitt's lymphoma; DLBCS=diffuse large cell lymphoma; DUSP16=dual specificity phophatase-16; EBV=Epstein–Barr Virus; FL=follicular lymphoma; HIV=human immunodeficiency virus; MCL=mantle cell lymphoma; MSP=methylation-specific PCR; MZL=marginal zone lymphoma.