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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Cancer Biol Ther. 2009 Dec 19;8(23):2275–2283. doi: 10.4161/cbt.8.23.10137

Figure 2. Comparative histology of the original patient tumors with initial passage and established xenografts of HNSCC.

Figure 2

Histologic sections of the original surgical specimen (SS), initial passage and established (estd) xenografts established in SCID mice are shown for three HNSCC samples. The samples represent SCC of the oral cavity, larynx and base of tongue. The degree of differentiation and keratinization was assessed using a grading scale as described in the Materials and Methods section. Initial passage and established xenografts from all three samples retained the histologic characteristics of the original surgical specimen.