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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Chem Biol Drug Des. 2010 May 4;76(1):1–9. doi: 10.1111/j.1747-0285.2010.00986.x

Figure 1.

Figure 1

The target site at the EGF receptor dimerization interface. A) Crystal structures of the extracellular domain of the EGF receptor homodimer (PDB:1MOX) and the dimerization arm (box). B) Critical residues Y246 and Y251 pack into adjacent pockets at the dimer interface.