Table 1. Recognition of different cancer cell lines by aptamers selected for adenocarcinoma.
Cancer | Cell lines | S1 | S6 | S11e | S15 |
---|---|---|---|---|---|
Adenocarcinoma (NSCLC) | A549 | +++ | ++++ | ++++ | ++++ |
Large cell carcinoma (NSCLC) | HLAMP | + | ++ | +++ | ++ |
Large cell carcinoma (NSCLC) | NCI-H460 | + | ++ | +++ | ++ |
Large cell carcinoma (NSCLC) | NCI-H299 | 0 | + | + | + |
Squamous carcinoma (NSCLC) | NCI-H520 | 0 | 0 | + | 0 |
Squamous carcinoma (NSCLC) | NCI-H157 | 0 | 0 | ++ | 0 |
Small-cell lung cancer | NCI-H446 | 0 | 0 | ++ | 0 |
Human cervical carcinoma | HeLa | 0 | 0 | 0 | 0 |
Human breast carcinoma | MCF7 | 0 | 0 | 0 | 0 |
Hepatocellular carcinoma | HepG2 | + | ++ | +++ | ++ |
Percentage: 0(<15%); +(10–35%); ++(35–60%); +++(60–85%); ++++(>85%).
NSCLC: Non-small-cell lung cancer.
Data from [21].