Table 2.

Up-regulation of parkin and pink1 in the DKO mutant background

Genotype	Adult viability*
UAS-parkin;;da-GAL4†/+	Viable
UAS-pink1;;da-GAL4/+	Viable
UAS-parkin;d72‡;da-GAL4 d93§/d93	Lethal
UAS-pink1;d72;da-GAL4 d93/d93	Lethal

*Flies were scored for viability 14d after the cross at 25 °C.

^†da-GAL4 drives expression ubiquitously.

^‡d72 denotes DJ-1a deletion allele.

^§d93 denotes DJ-1b deletion allele.