Fig. 3.

Oral anti (a)-CD3 + GC increases CD4⁺LAP⁺ cells and decreases NKT cells in MLN, spleen, and blood. The percentages of CD4⁺LAP⁺ T cells and NKT cells were measured by FACS analysis in MLN, spleen, and blood of ob/ob mice (10 per group) fed with a-CD3 + GC, a-CD3, GC, or PBS 5 days after the last treatment. The percentages of CD4⁺LAP⁺ T cells and NKT cells in a total of 1 × 10⁴ events are presented. The numbers shown on top of each data bar represent the total number of cells. These experiments were repeated twice with the same results. Error bars represent SD.