Table 3.
Effects of treatment with the total alkaloid fraction of Hygrophila auriculata on the biochemical parameters of CCl4 intoxicated rats
| Treatment | Dose | ASAT U/L | ALAT U/L | ALP U/L | Albumin g/L | Total bilirubin mg/dL | Total protein g/dL | TGL mg/dL | LDH U/L |
|---|---|---|---|---|---|---|---|---|---|
| Normal | - | 89.48 ± 0.537 | 60.65 ± 13.55 | 328.37 ± 2.102 | 3.283 ± 0.295 | 0.46 ± 0.04 | 7.385 ± 3.127 | 76.57 ± 0.22 | 258.49 ± 0.051 |
| CCl4 | 1ml/kg body wt | 170.04 ± 2.04a | 115.26 ± 12.18a | 593.19 ± 4.604a | 1.476 ± 0.104a | 0.98 ± 0.02a | 4.402 ± 1.42a | 28.44 ± 0.12a | 520.38 ± 0.04a |
| standard silymarin + CCl4 (1ml/kg body wt) | 250 mg/kg body wt | 80.87 ± 1.47c | 62.15 ± 10.97c | 358.32 ± 3.43c | 3.374 ± 0.324c | 0.44 ± 0.01c | 6.459 ± 2.47c | 68.02 ± 0.09b | 305.72 ± 0.012c |
| total alkaloid fraction + CCl4 (1ml/kg body wt) | 80 mg/kg body wt | 86.92 ± 1.29c | 64.55 ± 12.41c | 370.09 ± 2.394c | 3.368 ± 0.208b | 0.48 ± 0.013c | 6.202 ± 2.61c | 67.08 ± 0.17b | 312.59 ± 0.104c |
Number of animals (n=6).
a
= P < 0.001, when compared to the normal group.
b
= P < 0.01.
c
= P < 0.001, when compared to the CCl4 group.