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. Author manuscript; available in PMC: 2010 Jul 20.

Published in final edited form as: Neuropsychopharmacology. 2006 Nov 8;32(5):1098–1108. doi: 10.1038/sj.npp.1301228

Table 3.

Follow-Up Two-Way ANOVAs for Response Rates Within Each Nicotine Dose Condition

			Infusion lever^a			VS lever^b
Dose	Phase	Source	df	F	Sig.	df	F	Sig.
30 mg/kg/inf	FR1	Session	11	4.24	0.00^*	11	14.23	0.00^*
		Session^* group	22	3.37	0.00^*	22	3.26	0.00^*
		Error (session)	220			198
		Group	2	12.06	0.00^*	2	4.88	0.02^*
		Error	20			18
	FR2	Session	9	6.21	0.00^*	9	2.82	0.01^*
		Session^* group	18	0.75	0.76	18	0.70	0.81
		Error (session)	180			162
		Group	2	11.21	0.01^*	2	8.20	0.01^*
		Error	20			18
60 mg/kg/inf	FR1	Session	11	8.24	0.00^*	11	14.13	0.00^*
		Session^* group	22	2.66	0.00^*	22	2.13	0.01^*
		Error (session)	209			209
		Group	2	5.70	0.01^*	2	3.24	0.06
		Error	19			19
	FR2	Session	9	3.55	0.00^*	9	5.30	0.00^*
		Session^* group	18	1.06	0.40	18	1.98	0.01^*
		Error (session)	171			171
		Group	2	15.12	0.00^*	2	3.84	0.04^*
		Error	19			19
90 mg/kg/inf	FR1	Session	11	8.34	0.00^*	11	11.71	0.00^*
		Session^* group	22	2.40	0.00^*	22	3.51	0.00^*
		Error (session)	198			176
		Group	2	22.01	0.00^*	2	3.01	0.08
		Error	18			16
	FR2	Session	9	0.72	0.69	9	1.71	0.09
		Session^* Group	18	1.17	0.30	18	0.84	0.65
		Error (session)	162			144
		Group	2	13.22	0.00^*	2	10.95	0.00^*
		Error	18

FR=fixed ratio schedule of reinforcement.

^*

Indicates significant main effect or interaction according to a priori criterion, p≤0.05.

^a

Contrasts 2-Lever, NIC+VS, and NIC-Only groups.

^b

Contrasts 2-Lever, NIC+VS and VS-Only (0 μg/kg/infusion) groups.