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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Biomaterials. 2010 Apr 18;31(20):5418–5426. doi: 10.1016/j.biomaterials.2010.03.045

Figure 4. Endothelial rate of migration is differentially influenced by nano to micron scale topographic cuing.

Figure 4

Cumulative distance of at least 50 cells over a 12 hour period was determined using particle tracking within Zeiss Axiovision software for each cell line including HUVEC (A), HmVEC-d (B), HAEC (C) and HSaVEC (D). HAEC cells were the only cell line analyzed that did not demonstrate significant differences between planar control and topographically patterned substrates. Significant differences are marked as follows: * =<0.05, ** = p<0.01, *** = p<0.001. Note that no differences were seen on 400 nm pitch surfaces for all cell-types examined (Data shown as Mean ± SEM).