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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Immunol Rev. 2010 May;235(1):297–305. doi: 10.1111/j.0105-2896.2010.00891.x

Fig. 1. Enhanced IFN-γ production by memory-like NK cells is maintained for at least 4 weeks.

Fig. 1

Cytokine-activated (A) Ly5.1+ CFSE-labeled NK cells and control-treated (B) Ly5.2+ CFSE-labeled NK cells were adoptively co-transferred into a naive Ly5.2 host. Four weeks after adoptive transfer, NK cell were re-stimulated in vitro for four hours with IL-12 and IL-15. Three populations of NK cells were identified based on CFSE and Ly5.1 expression (left panel, gated on NK cells): (A) preactivated NK cells were significantly more likely to produce IFN-γ when compared to (B) control-transferred or (C) host NK cells (representative flow plots shown).