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Case no.6 demonstrating detection of DNA segment copy number changes on chromosome 7 and 11 using 21K BAC aCGH. Average log2 ratios (y-axis) were plotted for all clones based on chromosomal position (x-axis) with the blue bar demarcating the centromere. Horizontal red lines indicate the log2 ratio for each segment as segmented by Circular Binary Segmentation (CBS).
