Figure 2.

Expression of AKR1C3 in endometrial adenocarcinoma of endometrial type. (A) In this case of adenocarcinoma, there is no immumoreactiv-ity for AKR1C3 in the carcinomatous cells but enodothelial cells of blood vessels are immunoreactive (arrow). (B) Both nuclear and cytoplasmic immunoreactivity are demonostrated in blood vessels (arrow). (C) In this case of adenocarcinoma, there is widespread positive immunoreactivity with small clusters of non-immunoreactive area (arrow). (D) Small clusters of non-immunoreactive cells are present among positive cells. (E) In this case of adenocarcinoma, practically all carcinomatous cells are immunoreactive. (F) Both nuclear and cytoplasmic immunoreactivity are demonstrated. (Original magnification for panel A, C, and E is 10×, for panel B, D, and F is 60×).