Table 3.
Minor allele frequencies (MAF) of 38 gene polymorphisms for 234 people of southeastern Minnesota
Gene | Name | Rs | HW p value | MAF | Function |
---|---|---|---|---|---|
ADRA2C | ADRA2C-Del322-325 | 1 | 0.05 | Del-ins | |
ADRB3 | Trp64Arg | rs4994 | 0.41 | 0.09 | Non-synonymous |
ADRA2A | rs17128356 | 0.55 | 0.058 | intergenic | |
ADRA2A | rs7096359 | 1 | 0.083 | intergenic | |
ADRA2A | rs491589 | 0.62 | 0.156 | intergenic | |
ADRA2A | -1291(C-G) | rs1800544 | 0.88 | 0.295 | near gene |
ADRA2A | rs1800545 | 0.76 | 0.124 | 5’ UTR | |
ADRA2A | rs11195419 | 0.57 | 0.132 | 3’ UTR | |
ADRA2A | rs553668 | 0.81 | 0.16 | 3’ UTR | |
ADRA2A | rs3750625 | 0.49 | 0.053 | 3’ UTR | |
ADRA2A | rs602618 | 0.76 | 0.299 | intergenic | |
ADRA2A | rs34665740 | 0.23 | 0.034 | intergenic | |
UCP-2 | +3474 45bp-insdel | 0.62 | 0.24 | Del-ins | |
UCP-2 | Ala55Val | rs660339 | 1 | 0.423 | Non-synonymous |
UCP-2 | rs659366 | 0.89 | 0.372 | intergenic | |
UCP-3 | rs590336 | 0.15 | 0.447 | ||
UCP-3 | rs15763 | 1 | 0.25 | 3’ UTR | |
UCP-3 | rs647126 | 0.15 | 0.447 | 3’ UTR | |
UCP-3 | rs1685356 | 0.43 | 0.429 | near gene | |
UCP-3 | rs2632723 | 0.42 | 0.201 | near gene | |
UCP-3 | rs11235971 | 0.2 | 0.286 | near gene | |
UCP-3 | rs1626521 | 0.41 | 0.267 | near gene | |
UCP-3 | Tyr210 | rs2075577 | 0.11 | 0.404 | synonymous |
UCP-3 | rs2734827 | 0.064 | 0.357 | inton | |
UCP-3 | Tyr99 | rs1800006 | 0.3 | 0.256 | synonymous |
GNB3 | rs2269355 | 1 | 0.432 | intron | |
GNB3 | rs10849527 | 0.63 | 0.288 | intron | |
GNB3 | rs3759348 | 0.75 | 0.286 | near gene | |
GNB3 | rs4963517 | 0.6 | 0.429 | near gene | |
GNB3 | rs4963516 | 1 | 0.135 | near gene | |
GNB3 | Ile685Thr | rs1129649 | 0.57 | 0.346 | nonsense/missense |
GNB3 | rs1047776 | 0.62 | 0.073 | 3’ UTR | |
GNB3 | rs5439 | 0.45 | 0.096 | 3’ UTR | |
GNB3 | rs5440 | 0.52 | 0.487 | 3’ UTR | |
GNB3 | G814A (Gly272Ser) | rs5442 | 0.61 | 0.068 | Non-synonymous |
GNB3 | C825T (Ser275) | rs5443 | 0.76 | 0.303 | synonymous |
FTO | rs9939609 | 0.51 | 0.44 | intron | |
5-HTTLPR | LS/SS (-SLC6A4) | 44 bp ins | 0.69 | 0.41 | Del-ins |