Table 2.
MtDNA Variants in 1 Han Chinese Subject (II-1) With Hypertension
| Gene | Position | Replacement | Conservation (H/B/M/X)* | Previously Reported† |
|---|---|---|---|---|
| D-Loop | 73 | A to G | Yes | |
| 249 | DelA | Yes | ||
| 310 | T to CTC | Yes | ||
| 489 | T to C | Yes | ||
| 16145 | G to A | Yes | ||
| 16223 | C to T | Yes | ||
| 16298 | T to C | Yes | ||
| 16519 | T to C | Yes | ||
| 12S rRNA | 750 | A to G | A/A/G/A | Yes |
| 1438 | A to G | A/A/A/G | Yes | |
| 16S rRNA | 2706 | A to G | A/G/A/A | Yes |
| ND1 | 3552 | T to A | Yes | |
| NC2 | 4401 | A to G | A/A/A/A | No |
| ND2 | 4715 | A to G | Yes | |
| 4769 | A to G | Yes | ||
| 5262 | G to A (Ala to Thr) | A/M/I/F | Yes | |
| CO1 | 5993 | C to T | No | |
| 6338 | A to G | Yes | ||
| 6386 | C to T | Yes | ||
| 7028 | C to T | Yes | ||
| 7196 | C to A | Yes | ||
| ATP6 | 8584 | G to A (Ala to Thr) | A/V/V/I | Yes |
| 8701 | A to G (Thr to Ala) | T/S/L/Q | Yes | |
| 8860 | A to G (Thr to Ala) | T/A/A/T | Yes | |
| CO3 | 9540 | T to C | Yes | |
| 9545 | A to G | Yes | ||
| ND3 | 10398 | A to G (Thr to Ala) | T/T/T/A | Yes |
| 10400 | C to T | Yes | ||
| ND4 | 10873 | T to C | Yes | |
| 11447 | G to A (Val to Met) | V/V/I/V | Yes | |
| 11719 | G to A | Yes | ||
| 11914 | G to A | Yes | ||
| ND5 | 12705 | C to T | Yes | |
| 13263 | A to G | Yes | ||
| ND6 | 14318 | T to C (Asn to Ser) | N/N/D/S | Yes |
| Cytb | 14783 | T to C | Yes | |
| 15043 | G to A | Yes | ||
| 15301 | G to A | Yes | ||
| 15326 | A to G (Thr to Ala) | T/M/I/I | Yes | |
| 15487 | T to C | Yes |
*
Conservation of amino acid for polypeptides or nucleotide for rRNAs in human (H), bovine (B), mouse (M), and X laevis (X).