Table 4.

Association between sex hormone/SHBG levels and CRP (µg/ml) by treatment group

Hormones	Placebo		Estradiol
	β (SE) estimate*	p-value	β (SE) estimate*	p-value
Estrone (pg/ml)	0.01(0.01)	0.32	0.002(0.0005)	0.0003
Estradiol (pg/ml)	0.02(0.01)	0.09	0.007(0.002)	<.0001
Free estradiol (pg/ml)	0.93(0.47)	0.05	0.41(0.12)	0.001
Total testosterone (ng/dl)	−.02(0.01)	0.03	0.02(0.01)	0.27
Free testosterone (pg/ml)	−.02(0.05)	0.67	−.09(0.06)	0.12
Androstenedione (pg/ml)	−.0001(0.0004)	0.90	−.0002(0.0005)	0.67
DHEA (ng/ml)	−.10(0.06)	0.10	−.22(0.08)	0.006
SHBG (nmol/L)	−.02(0.006)	0.004	0.01(0.004)	0.002

^*β estimates are from generalized estimating equations models, adjusted for age and BMI.