Table 5.

Association between sex hormone/SHBG levels and homocysteine (mg/ml) by treatment group

Hormones	Placebo		Estradiol
	β (SE) estimate*	p-value	β (SE) estimate*	p-value
Estrone (pg/ml)	−.002(0.002)	0.35	−.002(0.0005)	0.001
Estradiol (pg/ml)	0.0001(0.007)	0.98	−.01(0.003)	0.0006
Free estradiol (pg/ml)	−.01(0.31)	0.96	−.48(0.15)	0.0009
Total testosterone (ng/dl)	−.02(0.01)	0.09	−.01(0.01)	0.38
Free testosterone (pg/ml)	−.09(0.06)	0.09	0.11(0.08)	0.18
Androstenedione (pg/ml)	0.0005(0.005)	0.36	−.0002(0.001)	0.71
DHEA (ng/ml)	0.01(0.08)	0.90	0.10(0.10)	0.31
SHBG (nmol/L)	0.003(0.63)	0.63	−.008(0.006)	0.14

^*β estimates are from generalized estimating equations models, adjusted for age, and BMI.