Table 2.
Effects of increasing renal pelvic pressure on contralateral urinary sodium excretion in CHF and Sham CHF rats during renal pelvic perfusion with vehicle and BQ123, 5 µM.
Renal Pelvic Perfusion |
Control | 8RPP 2.5 mmHg |
Control |
8RPP 7.5 mmHg |
|
---|---|---|---|---|---|
CHF, n=13 | Vehicle | 1.63±0.33 | 1.61±0.30 | 1.77±0.35 | 1.88±0.37 |
BQ123 | 1.84±0.29 | 1.93±0.29 | 1.99±0.31 | 2.23±0.39** | |
Sham CHF, n=13 | Vehicle | 1.09±0.29 | 1.28±0.33* | 1.09±0.28 | 1.37±0.31* |
BQ123 | 1.18±0.19 | 1.34±0.22* | 1.37±0.20 | 1.77±0.27* |
Values are means±SE in µmol·min−1·g−1
Control, average of control and recovery periods; 8RPP , increased renal pelvic pressure;
P<0.05
P<0.01 vs. control.