Figure 6.—

Extended LD surrounding AOP2 and AOP3. Pairwise linkage disequilibrium between SNPs within coding regions of query genes (AOP2, AOP3, MAM1, and MAM3) and SNPs within ±1 Mb of the AOP locus is shown as a heatmap with significantly strong to weak LD indicated by green to white, respectively. The top histogram shows the number of GSL phenotypes significantly associated with individual SNP in this region for both the 2007 and 2008 data sets. The right bar graph shows the minor allele frequency of each SNP within the query genes. The cladogram on the left indicates the hierarchical clustering of linkage patterns for each SNP position within the query genes.