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Blastomeres from the same cleavage-stage embryos were biopsied into individual cells and randomized to analysis by either FISH or microarray. Blastomeres from multiple embryos were randomized together so that the embryo specific origin of each blastomere was blinded. The paired randomized design controls for true mosaicism and the blinded analysis avoids bias in interpretation from knowledge of each blastomere's embryo of origin.
