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. 2010 Jun 3;25(8):1988–1995. doi: 10.1093/humrep/deq142

Table II.

Univariate and multivariate analysis of the association between live birth and clinical, sonographic and endocrinological parameters prior to start of ovarian stimulation, and type of gonadotrophin treatment in the entire group of normogonadotropic anovulatory patients (n = 335).

Parameter Univariate
Multivariate
OR 95% CI P OR 95% CI P
Clinical
 Female age (years) 0.91 0.84–0.98 0.015
 BMI (kg/m2) 1.01 0.95–1.08 0.673
 Waist-to-hip ratioa 1.15 0.90–1.48 0.271
 Menstrual cycle pattern 0.022 0.040
  Oligomenorrhea (reference) 1.00 1.00
  Amenorrhea 0.69 0.32–1.47 0.63 0.32–1.22
  Anovulatory cycles 0.33 0.15–0.73 0.45 0.23–0.88
 Duration of infertility (years) 0.71 0.56–0.91 0.007 0.78 0.64–0.95 0.013
 Previous pregnancy 0.77 0.43–1.41 0.402
 Failure to conceive on CC 0.87 0.49–1.54 0.632
 Failure to ovulate on CC 1.15 0.65–2.04 0.632
Sonographicb
 Antral follicle count 1.01 0.99–1.03 0.209
 Mean ovarian volume (cm3) 1.00 0.93–1.07 0.966
Endocrinologicalb
 LH (IU/l) 1.00 0.94–1.07 0.895
 FSH (IU/l) 0.83 0.69–0.99 0.034 0.86 0.74–1.01 0.062
 Estradiol (pmol/l)c 0.92 0.83–1.02 0.111
 Prolactin (μg/l) 1.01 0.98–1.03 0.696
 Androstenedione (nmol/l) 0.99 0.92–1.07 0.818
 Total testosterone (nmol/l) 0.91 0.57–1.44 0.678
 SHBG (nmol/l) 1.01 1.00–1.01 0.142
 Glucose, normald 2.16e 0.63–7.35e 0.219e
 Insulin, normald 1.11e 0.59–2.08e 0.756e
 Insulin-to-glucose ratio 0.94 0.83–1.07 0.331
Type of gonadotrophin
 HP-FSH versus rFSHf 0.84 0.37–1.89 0.674
 HP-hMG versus rFSHg 0.80 0.36–1.78 0.587

aSteps of 0.1.

bAt start of stimulation.

cSteps of 25 pmol/l.

dAs defined by central laboratory reference ranges.

eNormal versus abnormal.