Table II.
Parameter | Univariate |
Multivariate |
||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Clinical | ||||||
Female age (years) | 0.91 | 0.84–0.98 | 0.015 | |||
BMI (kg/m2) | 1.01 | 0.95–1.08 | 0.673 | |||
Waist-to-hip ratioa | 1.15 | 0.90–1.48 | 0.271 | |||
Menstrual cycle pattern | 0.022 | 0.040 | ||||
Oligomenorrhea (reference) | 1.00 | 1.00 | ||||
Amenorrhea | 0.69 | 0.32–1.47 | 0.63 | 0.32–1.22 | ||
Anovulatory cycles | 0.33 | 0.15–0.73 | 0.45 | 0.23–0.88 | ||
Duration of infertility (years) | 0.71 | 0.56–0.91 | 0.007 | 0.78 | 0.64–0.95 | 0.013 |
Previous pregnancy | 0.77 | 0.43–1.41 | 0.402 | |||
Failure to conceive on CC | 0.87 | 0.49–1.54 | 0.632 | |||
Failure to ovulate on CC | 1.15 | 0.65–2.04 | 0.632 | |||
Sonographicb | ||||||
Antral follicle count | 1.01 | 0.99–1.03 | 0.209 | |||
Mean ovarian volume (cm3) | 1.00 | 0.93–1.07 | 0.966 | |||
Endocrinologicalb | ||||||
LH (IU/l) | 1.00 | 0.94–1.07 | 0.895 | |||
FSH (IU/l) | 0.83 | 0.69–0.99 | 0.034 | 0.86 | 0.74–1.01 | 0.062 |
Estradiol (pmol/l)c | 0.92 | 0.83–1.02 | 0.111 | |||
Prolactin (μg/l) | 1.01 | 0.98–1.03 | 0.696 | |||
Androstenedione (nmol/l) | 0.99 | 0.92–1.07 | 0.818 | |||
Total testosterone (nmol/l) | 0.91 | 0.57–1.44 | 0.678 | |||
SHBG (nmol/l) | 1.01 | 1.00–1.01 | 0.142 | |||
Glucose, normald | 2.16e | 0.63–7.35e | 0.219e | |||
Insulin, normald | 1.11e | 0.59–2.08e | 0.756e | |||
Insulin-to-glucose ratio | 0.94 | 0.83–1.07 | 0.331 | |||
Type of gonadotrophin | ||||||
HP-FSH versus rFSHf | 0.84 | 0.37–1.89 | 0.674 | |||
HP-hMG versus rFSHg | 0.80 | 0.36–1.78 | 0.587 |
aSteps of 0.1.
bAt start of stimulation.
cSteps of 25 pmol/l.
dAs defined by central laboratory reference ranges.
eNormal versus abnormal.