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. Author manuscript; available in PMC: 2010 Jul 20.
Published in final edited form as: Microcirculation. 2010 Jul;17(5):333–347. doi: 10.1111/j.1549-8719.2010.00034.x

Figure 7. Vulnerability of Balb-like networks.

Figure 7

A, Percentage of arterial occlusions that are predicted to cause loss of perfusion and ischemia in a tissue, assuming 0–3 similar-diameter arteriole-to-arteriole collaterals are present. B, Predicted average percentage of tissue downstream of an occlusion. C, Schematic of the blood flow changes (left, arrows) and morphological changes (right) following arteriolar ligation of Balb/c (top) and C57Bl/6 (bottom) mice. D, Schematic of the development of muscle vasculature and subsequent responses to loss of perfusion and flow re-routing. Genes such as clic4 and vegfa have been shown to be involved in the formation of arteriole-to-arteriole collaterals.