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. 2010 Apr 21;83(2):185–194. doi: 10.1095/biolreprod.109.083287

FIG. 5.

FIG. 5.

Differential TIMP1 localization in the ovary after in vivo treatments. More TIMP1 protein was localized in the thecal cells of antral follicles in Endo rats (A) than in Sham rats (B). C) Treatment of Endo rats with a TIMP1 function-blocking antibody reduced TIMP1 localization to levels equal to Sham. D) Sham rats treated with TIMP1 had an increase in TIMP1 localization in the ovarian theca, providing further evidence that TIMP1 from the peritoneal cavity can sequester into the ovary to influence its function. The arrows indicate increased thecal localization of TIMP1 in A and D. Original magnification ×200.