Table 2. Logistic regression analysis of the association of a positive interleukin (IL)-2 ELISpot assay, interferon (INF)-γ ELISpot assay and tuberculin skin test with potential explanatory factors for the presence of positive results in tests for the immunodiagnosis of tuberculosis.
Covariates | IL-2 ELISpot assay | INF-γ ELISpot assay | Tuberculin skin test | |||
Crude OR (95% CI) | Adjusted OR (95% CI) | Crude OR (95% CI) | Adjusted OR (95% CI) | Crude OR (95% CI) | Adjusted OR (95% CI) | |
Exposure ≥100 hours | 2.5(0.3 23.0)p<0.001) | 1.7(0.2 18.0)p = 0.6 | 40.8(6.9 240.3)p<0.001 | 27.9(4.2 183.5)p = 0.001 | 19.3(2.7 137.5)p = 0.003 | 8.5(0.9 81.6)p = 0.06 |
BCG vaccination | 1.4(0.5 3.4)p = 0.51 | 1.2(0.4 3.2)p = 0.72 | 1.7(0.7 4.0)p = 0.21 | 1.36(0.4 4.4)p = 0.6 | 2.3(0.9 5.9)p = 0.07) | 2.3(0.7 7.3)p = 0.15 |
Age, years | 1.02(1.0 1.1)p = 0.3 | 1.02(1.0 1.1)p = 0.44 | 1.06(1.0 1.1)p = 0.008) | 1.06(1.0 1.13)p = 0.07 | 1.05(1.0 1.1)p = 0.02 | 1.05(1.0 1.1)p = 0.05) |
Sex, male | 0.8(0.1 4.5)p = 0.8 | 0.8(0.1 4.5)p = 0.8 | 1.1(0.2 5.1)p = 0.9 | 0.8(0.1 4.8)p = 0.72 | 1.05(0.3 2.5)p = 0.29 | 0.37(0.1 4.05)p = 0.41 |
*OR, odds ratio; CI, confidence interval.; BCG, Bacillus Calmette-Guérin.