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. 2010 Jul 20;5(7):e11670. doi: 10.1371/journal.pone.0011670

Table 2. Logistic regression analysis of the association of a positive interleukin (IL)-2 ELISpot assay, interferon (INF)-γ ELISpot assay and tuberculin skin test with potential explanatory factors for the presence of positive results in tests for the immunodiagnosis of tuberculosis.

Covariates IL-2 ELISpot assay INF-γ ELISpot assay Tuberculin skin test
Crude OR (95% CI) Adjusted OR (95% CI) Crude OR (95% CI) Adjusted OR (95% CI) Crude OR (95% CI) Adjusted OR (95% CI)
Exposure ≥100 hours 2.5(0.3 23.0)p<0.001) 1.7(0.2 18.0)p = 0.6 40.8(6.9 240.3)p<0.001 27.9(4.2 183.5)p = 0.001 19.3(2.7 137.5)p = 0.003 8.5(0.9 81.6)p = 0.06
BCG vaccination 1.4(0.5 3.4)p = 0.51 1.2(0.4 3.2)p = 0.72 1.7(0.7 4.0)p = 0.21 1.36(0.4 4.4)p = 0.6 2.3(0.9 5.9)p = 0.07) 2.3(0.7 7.3)p = 0.15
Age, years 1.02(1.0 1.1)p = 0.3 1.02(1.0 1.1)p = 0.44 1.06(1.0 1.1)p = 0.008) 1.06(1.0 1.13)p = 0.07 1.05(1.0 1.1)p = 0.02 1.05(1.0 1.1)p = 0.05)
Sex, male 0.8(0.1 4.5)p = 0.8 0.8(0.1 4.5)p = 0.8 1.1(0.2 5.1)p = 0.9 0.8(0.1 4.8)p = 0.72 1.05(0.3 2.5)p = 0.29 0.37(0.1 4.05)p = 0.41

*OR, odds ratio; CI, confidence interval.; BCG, Bacillus Calmette-Guérin.