Figure 3. LacZ-positive cells are predominantly localized in the retinal inner nuclear layer.

(A) The flat-mounted retina of a 3-month-old LRP5−/− mouse shows blue LacZ positive cells. (B) LacZ signals are observed in the cell bodies located in the inner nuclear layer of a 6-week-old LRP5−/− mouse. Cell nuclei were labeled with Fast Red. ONL: photoreceptor outer nuclear layer; OPL: outer-plexiform layer; INL: inner nuclear layer. Scale bar: 20 µm.