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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Toxicol Lett. 2010 May 31;197(3):163–168. doi: 10.1016/j.toxlet.2010.05.017

Fig.1. DEP increased the permeability of endothelial cells.

Fig.1

(A) HAEC cells were grown to confluence in transwell to form an endothelial monolayer. The cells were then treated with or without 50ug/ml DEP1 or DEP2 for 4 hours in the presence of 1ug/ml of Streptavidin-HRP. HRP activity from the bottom well was measured as the permeability of endothelial cells. (* vs. control, n=3, p<0.01; # DEP2 vs. DEP1, n=3, p<0.01). (B) Dose effect of DEP2 on HAEC permeability: HAEC were treated with indicated dose of DEP2 for 4 hours and HRP activity was measured as the permeability of endothelial cells. (n=3, ** vs. control, p<0.05; # # vs. control, p<0.01). (C) Time effect of DEP2 on HAEC permeability: HAEC were treated with 50ug/ml dose of DEP2 for 2, 4 and 6 hours, and HRP activity was measured as the permeability of endothelial cells. (C =Control)