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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2010 Apr 17;79(3):800–807. doi: 10.1016/j.ijrobp.2009.11.010

Table 6.

Generalized linear model of hematologic nadirs as a function of dosimetric parameters in the combined cohort

log (WBC Nadir) (k/μL)
log (ANC Nadir) (k/μL)
HGB Nadir (g/dL)
β 95% CI p β 95% CI p β 95% CI p
V10 −0.022 −0.04, −0.003 0.025* −0.029 −0.05, −0.005 0.019* −0.054 −0.12, 0.01 0.094
V20 −0.021 −0.03, −0.01 0.002* −0.027 −0.04, −0.01 0.001* −0.053 −0.10, −0.01 0.016*
V30 −0.011 −0.02, −0.0001 0.048* −0.014 −0.03, 0.001 0.034* −0.020 −0.06, 0.02 0.256
V40 −0.008 −0.02, 0.003 0.143 −0.011 −0.02, 0.001 0.069 −0.007 −0.04, 0.03 0.689
Mean Dose −0.350 −0.07, −003 0.033* −0.043 −0.08, −0.004 0.030* −0.069 −0.17, 0.03 0.189

CI: confidence interval; WBC: white blood cell count; ANC: absolute neutrophil count; HGB: hemoglobin; β: regression coefficient. Note: coefficients adjusted for effect of log(body mass index).

*

statistically significant