Table 7.
Acute hematologic toxicity in cervical cancer patients treated with chemoradiotherapy
| Study | Chemotherapy | External Beam Radiation Dose (Gy) | N | Grade ≥ 3 Hematologic Toxicity (%) |
|---|---|---|---|---|
| Whitney (1999)5 | HU | 40-60 | 191 | 41% |
| 5FU, CDDP | 40-60 | 177 | 7% | |
| Peters (2000)6 | CDDP | 49 | 127 | 38% |
| None | 49 | 116 | 3% | |
| Rose (1999)2 | CDDP | 40.8-51.0 | 176 | 23% |
| CDDP, 5FU, HU | 40.8-51.0 | 173 | 48% | |
| HU | 40.8-51.0 | 177 | 23% | |
| Pearcey (2002)42 | CDDP | 45 | 127 | 5% |
| None | 45 | 126 | 0% | |
| Keys (1999)1 | CDDP | 45 | 183 | 21% |
| None | 45 | 186 | 2% | |
| Torres (2008)8 | CDDP, 5FU | 45 | 76 | 24% |
| CDDP, 5FU | 45 | 115 | 41% | |
| CDDP | 45 | 111 | 23% |
5FU, 5-Fluorouracil; MMC, mitomycin-C; HU, hydroxyurea; CDDP, cisplatin