Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dnd1 and Dazl prevent miRNA-mediated repression in primary germ cells (PGCs). In somatic cells (top panel), the RISC complex directs the deadenylation and translational inhibition of target mRNAs. In PGCs, Dnd1 prevents the interaction between the RISC complex and its target mRNA (middle panel). In PGCs, Dazl antagonizes miRNA-mediated repression by inducing the polyadenylation of the target mRNA (bottom panel).
