Table 1.
Functions and target genes of zebrafish miRNAs
| miRNA | Targets | Function | Reference |
|---|---|---|---|
| miR-1 | Pfn21 Atp6v1ba Cnn3a |
Muscle development and Maintenance |
[36] |
| miR-8 | Nherf-1 | Osmotic stress response | [55] |
| miR-9 | Fgf8 Fgfr1 Cnpy1 Her5 Her9 |
Mid-hindbrain development |
[43] |
| miR-10 | HoxB3a HoxB1a |
Neural patterning | [44] |
| miR-15a-1 | - | Inner ear development | [83] |
| miR-18a | - | Inner ear development | [83] |
| miR-30a | - | Liver development | [84] |
| miR-125b | p53 | DNA-damage response | [56] |
| miR-126 | Spred1 PIK3R2 |
Vasculature development And maintenance |
[53] |
| miR-133 | Mps1 | Muscle development and maintenance Caudal Fin Regeneration |
[36] [63] |
| miR-138 | Aldh1a2 cspg2 |
Heart development | [41] |
| miR-140 | pdgfra | Neural crest migration | [47] |
| miR-144 | KLFD | Erythropoiesis | [85] [86] |
| miR-145 | Gata-6 | Gut development | [42] |
| miR-200 | - | Olfactory neurogenesis | [24] |
| miR-203 | Lef1 | Caudal fin regeneration | [64] |
| miR-214 | Su(fu) | Muscle development, Hedgehog signaling |
[45] |
| miR-375 | - | Pancreatic islet development |
[87] |
| miR-430 | Squint Lefty Nanos Tdr7 |
Mesendoderm induction, Nodal signaling Germ cell development |
[46] [65] |
| miR-451 | Gata-2 | Erythropoiesis | [88] |