Figure 1.
Chronic cocaine induces increased Kal7 expression in the NAc of Wt mice. A. The structure of Kal7 is diagramed (53) and the locations of the antibody site (JH2959; (35)) and the quantitative polymerase chain reaction (qPCR) primers are indicated. Twenty-four hours following 7 days of cocaine (20mg/kg) or saline injections, Kal7 protein (B; normalized to βIII tubulin – p=0.016) and mRNA (C; normalized to GAPDH – p=0.047) were significantly elevated. Primers used are listed in Supplementary Table 1.