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Lack of Kal7 does not affect acute locomotor response to cocaine. Using a randomized cross-over Latin-square design, Wt and Kal7KO animals were given the indicated doses of cocaine and examined in the open field. Two-way RM ANOVA revealed a main effect of treatment (p<0.0001) but no effect of genotype (p=0.318) or genotype x treatment interaction (p=0.267) [N=5/group].
