Table 2.
Other factors associated with risk of infections
| Any Infection | ||
|---|---|---|
| Variable | Relative Mean number of Infections (95% CI) |
p- value |
| Donor Age, years | ||
| 50 and older | 1.00 | 0.05§ |
| 40 – 49 | 0.88 (0.60 – 1.27) | |
| 30 – 39 | 0.84 (0.59 – 1.19) | 0.48* |
| 20 – 29 | 0.64 (0.45 – 0.91) | 0.32* |
| 0.01* | ||
| Donor/Recipient sex match | 0.03§ | |
| Female/Female | 1.00 | |
| Male/Male | 1.25 (0.93 – 1.68) | 0.13* |
| Female/Male | 1.10 (0.80 – 1.51) | 0.54* |
| Male/Female | 0.80 (0.56 – 1.14) | 0.21* |
| Donor/Recipient CMV Serostatus | 0.0005§ | |
| Positive/Positive | 1.00 | |
| Positive/Negative | 0.91 (0.64 – 1.29) | 0.59* |
| Negative/Positive | 1.48 (1.08 – 2.00) | 0.01* |
| Negative/Negative | 0.89 (0.61 – 1.30) | 0.56* |
| Bacterial Infections | ||
| Variable |
Ratio of Mean number of Infections* (95% CI) |
p- value |
| HLA Match | < 0.0001§ | |
| Well Matched | 1.00 | |
| Partially Matched | 1.65 (1.22 – 2.23) | 0.001* |
| Mismatched | 2.24 (1.59 – 3.13) | 0.0001* |
| Graft Type | 0.0007 | |
| PBSC | 1.00 | |
| Marrow | 0.61 (0.46 – 0.81) | |
| Viral Infections | ||
| Variable |
Ratio of Mean number of Infections* (95% CI) |
p- value |
| Donor/Recipient sex match | ||
| Female/Female | 1.00 | |
| Male/Male | 5.11 (1.78 – 14.42) | 0.002* |
| Female/Male | 3.31 (1.08 – 9.98) | 0.03* |
| Male/Female | 2.84 (0.90 – 8.80) | 0.07* |
| Donor/Recipient CMV Serostatus | ||
| Positive/Positive | 1.00 | |
| Positive/Negative | 1.13 (0.46 – 2.73) | 0.79* |
| Negative/Positive | 2.14 (1.03 – 4.40) | 0.04* |
| Negative/Negative | 0.30 (0.10 – 0.92) | 0.04* |
§
p-value of overall test
*
Compared to the reference group rate 1.0