Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
PTSD symptoms
RCT	60 people with PTSD	Mean total 8-item PTSD scale (TOP-8) score 5 months 5.23 with sertraline 50–100 mg daily 4.35 with nefazodone 200–400 mg daily	P = 0.36 The results of this RCT should be interpreted with caution because, despite randomisation, people taking sertraline had significantly higher baseline TOP-8 scores than people taking nefazodone		Not significant
RCT	37 people with PTSD	Change in Clinician Administered PTSD Scale (change from baseline) from 73.8 to 29.1 with sertraline (mean dose 153 mg/day) from 68.9 to 28.8 with nefazodone (mean dose 463 mg/day)	Reported as not significant P value not reported		Not significant