Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
PTSD symptoms
Systematic review	33 people Data from 1 RCT	Severity of self-reported PTSD symptoms 8 weeks with amitriptyline with placebo Absolute results not reported	SMD –0.90 95% CI –1.62 to –0.18	Effect size not calculated	amitriptyline
Systematic review	41 people Data from 1 RCT	Severity of self-reported PTSD symptoms 8 weeks with imipramine with placebo Absolute results not reported	SMD –0.24 95% CI –0.86 to +0.38		Not significant