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. 2010 Feb 3;2010:1005.
Ref (type) Population Outcome, Interventions Results and statistical analysis Effect size Favours
Proportion of people with PTSD

RCT
3-armed trial
48 people admitted to a surgical trauma centre with severe injuries Proportion of people diagnosed with PTSD (assessed using various scales) 4 months
2/10 (20%) with gabapentin (initially 300 mg three times daily increasing to 400 mg three times daily over 2 days)
4/16 (25%) with placebo

Significance not assessed
People with and without risk factors for PTSD after injury were enrolled in the RCT
The RCT may have been underpowered to detect clinically meaningful differences between groups