Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Proportion of people with PTSD | |||||
RCT 3-armed trial |
48 people admitted to a surgical trauma centre with severe injuries |
Proportion of people diagnosed with PTSD (assessed using various scales)
4 months
2/10 (20%) with gabapentin (initially 300 mg three times daily increasing to 400 mg three times daily over 2 days) 4/16 (25%) with placebo |
Significance not assessed People with and without risk factors for PTSD after injury were enrolled in the RCT The RCT may have been underpowered to detect clinically meaningful differences between groups |