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. 2010 Apr 9;17(8):550–558. doi: 10.1038/cgt.2010.10

Figure 6.

Figure 6

Therapeutic effects of oncolytic MVs for mesothelioma xenografts. Mesothelioma H513 cells were inoculated into the flanks of nude mice. The efficacy of MVs was compared by tumor growth (a) and survival (b). MV with mIFNβ expression arrested tumor growth. The experiment was repeated in SCID mice bearing mesothelioma H513 cells. Both tumor growth (data not shown) and survival (c) showed the superiority of MV-mIFNβ. Mesothelioma H2373 cells were established in the peritoneum of nude mice to mimic the human conditions. MV-mIFNβ significantly extended the survival of mice (d). *P<0.05; **P<0.01; #P<0.001.