• There is an ongoing effort to promote standardization and validation of outcomes for asthma–related research.38, 63-66
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• The TSLP gene is associated with self-reported doctor-diagnosed asthma11
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• The current HEDIS criterion of asthma quality of care (at least 1 controller-medication filling) is less predictive of a good clinical outcome than a controller-to-total asthma medication ratio of at least 50%17
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• Inhaled mannitol is a diagnostic test with high specificity and is best used to diagnose asthma, while methacholine and histamine bronchoprovocation tests are best used to rule out asthma25
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• FENO was not predictive of maximum symptom days reported by adolescents21
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• Total IgE was associated only with self-reported asthma among persons with positive allergen specific IgE and has no role as a biomarker for asthma in the general population22
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• The placebo effect has its greatest influence on self-reported outcomes rather than measures of lung function38
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• Achieving health equity will require interventions at many levels with attention to patient and provider beliefs, patient-provider communication, social and financial barriers to access, and patient poverty38, 63-66
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