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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Curr Biol. 2010 Feb 11;20(4):316–321. doi: 10.1016/j.cub.2009.12.034

Fig. 3.

Fig. 3

Expression of Bmal2 does not rescue the rhythmicity of B1ko SCN or lung tissues in vitro, but can rescue liver rhythmicity after dexamethasone (DEX) stimulation. Panels A, C, E show the raw data of luminescence from tissues of PmPer2∷mPer2-Luc knockin mice monitored in vitro. Tissue explants were dissected on Day 0 and recorded with a LumiCycle apparatus. Dark blue: WT; Magenta: Bmal2 Tg; Black: Bmal1ko; Light blue: Bmal1ko/Bmal2Tg. Panels B, D, F show the period analyses of those data (AR = arhythmic), plotted as means ± SD (N≥3, * p<0.05 by two-tailed T test).

A/B. suprachiasmatic nuclei (SCN) slices.

C/D. lung slices.

E/F. liver slices; + DEX (100 nM) on Day 8. In panel F, blue histograms represent the recording interval prior to DEX treatment (for WT vs. B2Tg, p = 0.11), and red histograms represent the interval during the DEX treatment.