Table 3.
Gene expression for hEBD LVEC cells exposed to SMF for five days (i.e., Group 3) compared to control cells incubated without SMF exposure (Group 1).
| Affymetrix Probeset ID | Gene Designation | Gene Symbol | Ratio | Average Signals | |
|---|---|---|---|---|---|
| (+ or -) fold-regulation | Control | Experimental | |||
| Up-regulated genes: | |||||
| 242517_at | G protein-coupled receptor 54 | GPR54 | (+) 7.84 | 60.1 | 470.7 |
| 1554452_a_at | hypoxia-i hypoxia-inducible protein 2nducible protein 2 | HIG2 | (+) 4.40 | 328.9 | 1446.4 |
| 205493_s_at | dihydropyrimidinase-like 4 | DPYSL4 | (+) 4.17 | 184.1 | 767.3 |
| 226682_at | hypothetical protein | LOC283666 | (+) 3.91 | 391.7 | 1530.5 |
| 226431_at | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 13 | ALS2CR13 | (+) 3.79 | 80.9 | 306.4 |
| 232068_s_at | toll-like receptor 4 | TLR4 | (+) 1.58 | 195.4 | 309.5 |
| Down-regulated genes: | |||||
| 217967_s_at | chromosome 1 open reading frame 24 | C1orf24 | (-) 7.60 | 848.5 | 111.7 |
| 220892_s_at | phosphoserine aminotransferase 1 | PSAT1 | (-) 4.72 | 2701.9 | 572.5 |
| 205047_s_at | asparagine synthetase | ASNS | (-) 4.64 | 2327.5 | 501.5 |
| 210587_at | inhibin, beta E | INHBE | (-) 4.12 | 176.6 | 42.8 |
| 204475_at | matrix metallopeptidase 1 (interstitial collagenase) | MMP1 | (-) 3.98 | 112.8 | 28.3 |
| 205207_at | interleukin 6 (interferon, beta 2) | IL-6 | (-) 3.23 | 513.2 | 158.9 |