Table 2.
Biological processes over-represented (p < 0.05) in domesticated G. hirsutum and domesticated G. barbadense relative to their wild forms.
| Domesticated species | GO term | |
|---|---|---|
| up-regulated | down-regulated | |
| G. hirsutum | antioxidant activity (Chl-APX, GST, CAT, TRX) | regulation of O2-/H2O2 production process (NADPH oxidase) |
| glutathione transferase activity (GSTs) | glycolate oxidase activity (GOX) | |
| Glycoside hydrolase activity(GLH) | cyclin-dependent protein kinase inhibitor activity | |
| peroxidase activity (APX, GST, CAT) | jasmonic acid and ethylene-dependent systemic resistance | |
| glutathione S-conjugate-exporting ATPase activity | ||
| removal of superoxide radicals (TRX) | ||
| oxidoreductase activity, acting on peroxides (APX, GST, CAT) |
||
| voltage-gated calcium channel activity (two pore Ca+ channels) |
||
| G. barbadense | response to stress (ESP, PRX, GH3-like) | superoxide dismutase activity (Cu/Zn SOD) |
| peroxidase activity (PRX) | carotenoid biosynthetic process (GPS) | |
| antioxidant activity (Chl-APX, PRX) | ent-kaurene oxidase activity (CYP450) | |
| regulation of epoxide hydrolase activity (EPH) | oxygen and reactive oxygen species metabolic process (SOD) | |
| voltage-gated calcium channel activity (two pore Ca+ channels) |
photosystem II reaction center | |
| MAP kinase activity (MAPK1, WIPK) | ||
| receptor signaling protein serine/threonine kinase activity (MAK, MAPKs) |
||
| jasmonic acid mediated signaling pathway (GH3- -like) |
||
| glycolate oxidase activity (GOX) | ||
Key genes are shown in parentheses (a complete list can be viewed in Additional file 5).
Abbreviations: Chl-APX – Thylakoid-bound ascorbate peroxidase;, GST – Glutathione S-transferase;, CAT – Catalase, TRX – Thioredoxin reductase; GLH – Glycoside hydrolase; APX – Ascorbaste peroxidase; PRX – Peroxidase; GOX – Glycolate oxidase; EPH – Epoxide hydrolase; MAPK – Mitogen-activated protein kinase; SOD – Superoxide dismutase; ESP – Ethylene signaling protein; GPS – geranylgeranyl pyrophosphate synthase.