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. Author manuscript; available in PMC: 2010 Jul 21.
Published in final edited form as: Cancer Ther. 2009 Apr 14;7(A):254–267.

Table 4.

Current use of chemokinesin cancer therapy

Chemokine Target Antagonist/Agonist Cancer Clinical Trial Status
CXCR4 AMD3100 Leukemia and Lymphoma Phase II
CXCL12 CTCE-9908 Late stage ovarian, breast, lung, colorectal, melanoma, gastric Phase I/II
CCL5 Met-CCL5 Breast Cancer Pre-clinical
CCR5 TAK-779 Multiple Myeloma, Prostate Pre-clinical
CXCR2 AZ10397767 Prostate Pre-clinical
SB225002 Esophageal
CCR2 MLN1202 Breast Pre-clinical