Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	76 people with tinnitus considered to be at high risk of developing severe and disabling tinnitus	Adverse effects 16 weeks with sertraline (25 mg/day for 1 week followed by 50 mg/day for 15 weeks) with placebo	The RCT may have been underpowered to detect a clinically meaningful difference between groups