Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Depression
Systematic review	152 people 4 RCTs in this analysis	Symptoms of depression with CBT with placebo Absolute results not reported	SMD +0.29 95% CI –0.04 to +0.63		Not significant
Quality of life
Systematic review	126 people 3 RCTs in this analysis	Quality-of-life scores with CBT with placebo Absolute results not reported	SMD 0.7 95% CI 0.33 to 1.08	Effect size not calculated	CBT
Tinnitus annoyance
Systematic review	269 people 8 RCTs in this analysis	Reduction in subjective tinnitus annoyance 3 months or more post treatment with CBT (combination of different psychotherapeutic approaches) with placebo Absolute results not reported	SMD 0.83 95% CI 0.82 to 0.84 The review had important flaws in its methods, compromising its validity (see further information on studies for more details)	Effect size not calculated	CBT