Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Symptom improvement
RCT	190 people with active psoriatic arthritis and psoriasis with at least 3% involvement	Proportion of people with at least a 75% improvement in Psoriasis Area and Severity Index score 17% with oral leflunomide (100 mg/day loading dose followed by 20 mg/day) 8% with placebo Absolute numbers not reported	P <0.05	Effect size not calculated	leflunomide