Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Ulcer recurrence | |||||
Systematic review |
2509 people 27 RCTs in this analysis |
Recurrence
14% with eradication treatment 64% with no treatment |
RR 0.20 95% CI 0.15 to 0.26 Results were heterogeneous because of differing eradication regimens and lengths of follow-up |
Moderate effect size | eradication treatment |
Systematic review |
531 people 5 RCTs in this analysis |
Ulcer recurrence
8% with eradication treatment containing proton pump inhibitors 65% with no treatment |
RR 0.14 95% CI 0.09 to 0.20 |
Large effect size | eradication treatment containing proton pump inhibitors |