Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Peptic ulcers | |||||
RCT |
100 H pylori-positive people requiring NSAID treatment and without any history of peptic ulceration or gastric surgery |
Peptic ulcer
8 weeks
3/45 (7%) with 1-week triple eradication regimen 12/47 (26%) with no eradication treatment |
P = 0.01 |
Effect size not calculated | triple eradication regimen |
RCT 4-armed trial |
832 people with H pylori and no history of ulcer, and requiring treatment with an NSAID |
Peptic ulcers
5 weeks
2/161 (1%) with 1-week triple eradication regimen 10/171 (6%) with placebo for 5 weeks |
P <0.05 for 1-week triple eradication regimen v placebo Analysis not by intention to treat |
Effect size not calculated | triple eradication regimen |
RCT 4-armed trial |
832 people with H pylori and no history of ulcer, and requiring treatment with an NSAID |
Peptic ulcers
5 weeks
2/173 (1%) with 1-week triple eradication regimen plus 4 weeks of omeprazole 10/171 (6%) with placebo for 5 weeks |
P <0.05 for 1-week triple eradication regimen plus 4 weeks of omeprazole v placebo Analysis not by intention to treat |
Effect size not calculated | triple eradication regimen |