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. 2009 Oct 1;2009:0406.
Ref (type) Population Outcome, Interventions Results and statistical analysis Effect size Favours
Peptic ulcers

RCT
100 H pylori-positive people requiring NSAID treatment and without any history of peptic ulceration or gastric surgery Peptic ulcer 8 weeks
3/45 (7%) with 1-week triple eradication regimen
12/47 (26%) with no eradication treatment

P = 0.01
Effect size not calculated triple eradication regimen

RCT
4-armed trial
832 people with H pylori and no history of ulcer, and requiring treatment with an NSAID Peptic ulcers 5 weeks
2/161 (1%) with 1-week triple eradication regimen
10/171 (6%) with placebo for 5 weeks

P <0.05 for 1-week triple eradication regimen v placebo
Analysis not by intention to treat
Effect size not calculated triple eradication regimen

RCT
4-armed trial
832 people with H pylori and no history of ulcer, and requiring treatment with an NSAID Peptic ulcers 5 weeks
2/173 (1%) with 1-week triple eradication regimen plus 4 weeks of omeprazole
10/171 (6%) with placebo for 5 weeks

P <0.05 for 1-week triple eradication regimen plus 4 weeks of omeprazole v placebo
Analysis not by intention to treat
Effect size not calculated triple eradication regimen